Palo santo is a tree that’s native to Peru, South American. It’s mainly used to clear negative energy and to repel mosquitos. The wood is burned as incense. As it burns, it releases aromatic smoke into the air that makes you feel calm and relax. The aroma of palo santo is relaxing, so it’s commonly used to ease stress. It’s thought to have a purifying, cleansing effect on the body and mind.